How Many Treatments Are Needed? And How Often?

The anesthetic in the solution used during Prolotherapy sessions often provides immediate pain relief. The pain relief may continue after the effect of the anesthetic subsides due to the stabilizing of the treated joints because of the inflammation caused by the Prolotherapy injections.

This pain relief normally continues for a few weeks after the first treatment.
Between the second and fourth weeks the initial stabilization induced by the Prolotherapy subsides, and because the initial growth of ligament tissue is not complete, some of the original pain may return during this "window period" of healing.

Follow-up is recommended four weeks after each treatment to ensure an accurate assessment of results, avoiding an evaluation of a patient during the "window period."

Prolotherapy is performed every four weeks because most ligaments heal over a four week period.
As healing progresses, the quantity of injections required per treatment usually decreases. The pain generally continues to diminish with each treatment unless it is an acute injury which may heal in only two to three weeks after Prolotherapy.